In the 1980s, research on monoclonal antibodies—antibodies mass produced in a laboratory to target a single antigen—generated excitement for their potential applications in fighting disease, especially cancer. However, their effectiveness in disease treatment has been limited. Today, a much smaller type of monoclonal antibody called a nanobody is being researched to treat diseases such as cancer and Alzheimer's. Nanobodies were discovered during unrelated research on what animal?
Back in the day
The Anglo-American Convention was a treaty signed in 1818 between the US and UK resolving their standing border issues and allowing for joint rights to the Oregon Country. Though it marked the beginning of improved relations between the two countries, tensions remained over the shared territory in Oregon. The British-chartered Hudson's Bay Company had already established a trading network there and sought to exclude US fur traders. What harsh policy did they implement to ward off competition?
Born on a day like today
Rimbaud may have put down his pen when he was just 19 to lead an international vagabond life as a merchant and trader, but in his few years as a poet, the precocious young Frenchman managed to create a literary legacy that would have a lasting influence on the symbolists and subsequent modern poets. He put his verbal virtuosity on display in works like "The Drunken Boat," A Season in Hell, and Illuminations. Who shot and wounded Rimbaud during one of their many lovers' quarrels?